Role of Brain Insulin Resistance in the Pathogenesis of Alzheimer's Disease.

Alzheimer's disease (AD) is the most common type of dementia,in which brain insulin resistance (BIR) plays a key role.BIR affects the response of brain cells to insulin and is associated with cognitive decline and pathological features of AD.This study explores the role of BIR in the pathogenesis of AD and evaluates potential treatment strategies,aiming to provide new directions for the prevention and treatment of AD. 阿尔茨海默病(AD)是最常见的痴呆类型,脑胰岛素抵抗(BIR)在其中扮演关键角色。BIR影响脑细胞对胰岛素的反应,与AD的认知功能下降和病理特征相关。本研究主要探讨BIR在AD发病机制中的作用,并评估潜在治疗策略,旨在为AD的预防和治疗提供新的方向。.